Publication Details

ASSESSMENT OF VASPIN AND RISK FACTORS IN RELATION WITH DIABETIC MELLITUS TYPE II
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	Type:
	General Speciality:
Arshad Noori Al-Dujaili	Author Name:
, Adhraa Baqir Hassan and Najlaa Saleh Mahdi	Co Authors Names:
RJC	Publisher Name:
http://www.rasayanjournal.com
2016	Publication Year:
Abstract Visceral adipose tissue-derived serine protease inhibitor (Vaspin) is a novel adipocytokine. Several studies have indicated that Vaspin may exert an important role in the development of metabolic disorders. The study was carried out from February 2013 to July 2013. The age of patients and control groups were range of 35-65y. The concentration of fasting blood glucose, cholesterol, triglyceride, LDL, VLDL, HDL, Vaspin and BMI were estimated in patients and control groups. This study was conducted on randomly selected 68 Type-2 diabetic patients (27 Males and 41 Females) attending the diabetes mellitus center in Al-Sadder Teaching City in Al-Najaf province, Iraq and a group of 20 apparently healthy subjects (10 Males and 10 Females) were included as a control group. Those parameter were higher in diabetic patients than in control group (P<0.05) in fasting blood glucose, cholesterol, triglyceride, LDL, VLDL and Vaspin levels in patients compared with control groups. The results revealed that Vaspin not significant difference (p>0.05) in patients and control groups at different ages. The results also revealed that Vaspin level increase significantly (P<0.05) in males than females in both patients and control groups. The results also revealed a significant increase (P<0.05) in BMI in patients compared with control groups. The results also show that Vaspin concentration increase significantly (P<0.05) with increasing BMI in males than females compared with control groups. The results have been shown significant positive correlation (P<0.05) between Vaspin, FBG, cholesterol, triglyceride, LDL and VLDL in patients (males and females), while significant negative correlation (P<0.05) was observed between Vaspin and HDL in patients (males and females). The present study concluded that Vaspin level was a marker for detection and diagnosis of diabetic patients Type-2, as you did not find significant difference between diabetic groups and control one, this conclusion is not justified. Keywords: diabetes mellitus, Risk Factors and Vaspin.