Abstract

Series bio - compounds prepared in this work which bearing bio – nuclei like thiazole ring via cyclization by acid or azotation reaction in cold medium or condensation by refluxing process , some these compounds included two process at same compound like formazan compound [9 and 10].All formatted compounds [1-10] were identified by using (TLC) and techniques((FT.IR ,1H.NMR ,13C.NMR ,Chromatography Analysis)) ,then studying((biological activity studying , chromatography behavior , studying of physical characterization and other analytical studies like solubility in various solvents )) .