Abstract

Streptococcus mutans are believed to be the principal etiological agent of human dental caries. It has developed multiple mechanisms to colonize the tooth surface and has become a significant species in cariogenic biofilm. Microbial biofilm are more resistant to antimicrobial agents and therefore more difficult to control. In this article the correlation between biofilm forming and antibiotic susceptibility of S. mutans isolates was studied. We studies S. mutants isolated from dental caries identification by VITEK-2 compact system and antibiotics susceptibility by disk diffusion method. Detection of biofilms formation was followed by (quantifying bacterial adhesion test). The results showed S. mutants the high percentage (71.4%) in comparison with the other streptococcus species from total dental caries samples. Out of 54 (90%) S. mutants have ability to forming biofilm. No significant difference among positive and negative S. mutants isolated were found regarding to antibiotics susceptibility. The high over all proportion of S. mutans produce biofilm. S. mutans biofilm have been showed to be significantly more resistance to antibiotics.