Benner
   
hawraa mohammed sharba ( Lecturer )
College Science - Chemistry
[email protected]
07801554245
 
 
 
SYNTHESIS AND CHARACTERIZATION OF NOVEL 1,3-OXAZEPINE DERIVATIVES FROM AMINOPYRAZINE
Type:
General Speciality:
Hawraa Mohammed Sadiq Author Name:
Co Authors Names:
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES Publisher Name:
Volume 6, Issue 5, 186-198 SJIF Impact Factor 6.647 ISSN 2278 – 4357 Research Article  
2017 Publication Year:

Abstract

In this work new 1,3-oxazepine subsidiaries have been readied, by two stages: The initial step incorporate amino gathering of the 2-aminopyrazine was dense with various fragrant aldehydes within the sight of supreme ethanol to give novel Schiff bases subordinates [A1 – A5] separately. The second step, the subsequent imines subordinates [A1-A5] were responded with maleic anhydride and phathalic anhydride in dry toluene to give new 1,3-oxazepine-4,7-dione ring subsidiaries [B1a-B5a] and [B1b-B5b] individually scheme[I]. Every one of these mixes were described by liquefying focuses and FT.IR spectroscopy, several of them were portrayed by 1H-NMR spectroscopy and C.H.N. S. examination.