Abstract

Abstract— The protective effect of Leek (Allium ampeloprasum) extract against testicular toxicity induced by carbon tetrachloride CCL4 was studied. The experiment was conducted on 36 male rats distributed randomly into 6 groups of 6 animals: group (1) was kept as a normal control which received distilled water; rats of groups (2) and (3) were given only Leek extract only in a dose 200 and 400 mg/kg; and groups (4,5,6) received CCL4 at a concentration of 1 ml/L by oral administration for induction of toxicity on rats. Groups 5 and 6 received Leek extract 200 and 400 mg/kg with CCL4 respectively. Results showed that oral administration of Leek extract in rats with testicular toxicity by CCL4 increased the weight of testes and accessory genital glands, sperm motility, count and viability, serum testosterone, luteinizing hormone and follicle stimulating hormone. It could be concluded that treatment with Leek extract produced a protective effect against toxicity induced by CCL4 in the male rats. Index Terms— Allium ampeloprasum, CCL4, Male fertility, Rat, .