Abstract

In the present study, the aqueous extract of SolanumNigrum used to synthesize AgNPs by the reduction of aqueous silver metal ions. The synthesized silver nanoparticles were characterized by UV spectroscopy, FTIR, XRD, SEM and TEM image shows uniformly distributed spherical, hexagonal and triangular in shape nanoparticles. The antifungal effects of these nanoparticles were studied against Aspergillusfumigatus, Aspergillusnidulans, and Canididaalbican. Transmission electron microscopy (TEM) measurements indicated that the newly formed nanoparticles were polydispersed with spherical, triangular, tetragonal, pentagonal, hexagonal and rod shapes. Crystalline nature of the nanoparticle in the face centered cubic (fcc) structure are confirmed by the peaks in the XRD pattern corresponding to (101), (98), (111) planes. Fourier Transform Infra-Red (FT-IR) spectroscopy analysis showed that the synthesized nanoparticles were capped with bimolecular compounds which are responsible for the reduction of silver ions. The present study indicates that Ag-NPs have considerable antifungal activity in comparison with standard antifungal drug, and hence further investigation for clinical applications is necessary.