Abstract

This research aims to enhance breast radiotherapy by increasing sensitivity enhancement ratio (SER). SER is the ratio of survival cells to initial cells for irradiation without and with NPs. The direct injection of nanoparticles into breast tumor considered a perfect method to increase SER. In this study AuNPS, GdNPs, AgNPs and TiNPs were used as radio-sensitizing agents to increase SER. The contrast agent loaded to breast tumor interacts with x-ray photons whose energy ranged from 2MeV to 20 MeV this led to enhance breast radio-sensitivity by increasing the absorbed dose due to the presence of high absorption coefficient elements. In this research, we get average SER from 10.79 to 13.50 depending on the type of contrast agent and x-ray energy.