الخلاصة

Abstract : The present study included 60 samples collected from patients suffering of thalassemia who attended to Thalassemia Center in Al-Zahraa hospital for birth and children in Al-Najaf governorate during the period from February to august-2014. All Subjects employed in this study were selected to confirm the presence or absence of antibodies, both alloantibodies or autoantibodies include coomb’s test in case of Positive DAT (direct anti globin test) and, IDAT(In direct anti globin test) for antibodies detection. Samples of blood were treated to tests of blood bank procedure for observed of antibodies. The study discovered infect in 32 male (53.3%) with was in28 female as (46.4) and 14 patients had autoantibodies as (23.3%) while patients have alloantibodies 24(40%). the goal of this research was to limit the prevalence of R.B.C autoantibodies and alloantibodies between frequency transfused thalassaemic patients and factors that contributed to its development. Keywords : Autoantibodies , epitopes , DAT, EDTA, Alloantibodies