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Comparative Study Between The Clinical Effects of Glucosamine/Gingko Biloba & Glucosamine/Chondroitin in Treatment of Knee Osteoarthritis


 
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1. Title Title of document Comparative Study Between The Clinical Effects of Glucosamine/Gingko Biloba & Glucosamine/Chondroitin in Treatment of Knee Osteoarthritis
 
2. Creator Author's name, affiliation, country Mohammed Al-Rekabi
 
3. Subject Discipline(s)
 
3. Subject Keyword(s)
 
4. Description Abstract

Abstract:
Aim: This study was designed to investigate the effect of two widely used combinations,
glucosamine/chondroitin and glucosamine/ginkgo biloba on the clinical picture of patient with
osteoarthritis(OA).
Methods: Fifty one (51) osteoarthritis patients ( 21 male and 30 female) were participated in this research
depending on certain selection criteria. The selected patient were randomly allocated into two groups: group
A includes 22 ( 9 male and 13 female) patients treated with a combination of glucosamine /gingko biloba
( 500/ 50 mg twice daily ) for six weeks whereas group B includes 29 (12 male and 17 female) patients
treated with a combination of glucosamine/chondroitin (500/ 400mg twice daily ) for six weeks . Effects of
drug treatment were assessed each seven days by clinical evaluation and direct interview with patients
through a questionnaire method known as Knee Injury and Osteoarthritis Outcome Score (KOOS).
Results: It was found that all components of KOOS including pain score, symptoms score, activity of daily
living (ADL), quality of life (QOL) and sport & recreation scores were significantly elevated (improved) in
both combinations, however, glucosamine /gingko biloba showed a better improvement when statistically
compared with the combination of glucosamine/chondroitin.
Conclusions: It is concluded from this study that the glucosamine sulfate is more clinically useful for OA
when combined with gingko biloba than when it is combined with chondroitin.
Recommendations: A large scale cohort study is recommended to ensure the clinical findings.
Key words: Osteoarthritis, Glucosamine sulfate, Chondroitin sulfate, Gingko biloba, Knee joint and
osteoarthritis outcome score
 
5. Publisher Organizing agency, location University of Kufa
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2015-11-17
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier http://www.uokufa.edu.iq/journals/index.php/kjns/article/view/4037
 
11. Source Title; vol., no. (year) Kufa Journal for Nursing Sciences; Vol 4, No 2 (2014)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)